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Drug Class and Mechanism: Clomicalm is a tricyclic antidepressant. Clomicalm affects chemicals in the brain that may become unbalanced leading to behavioral problems in dogs. Clomicalm is used in dogs to treat separation anxiety. Clomipramine is sometimes used to treat aggression and obsessive-compulsive disorders such as tail chasing. Clomicalm may also be used for purposes other than those listed in this guide.

Missed Dose: If you miss to give a dose of Clomicalm, give it as soon as possible. If it is almost time for your pet to take the next dose, skip the dose and go back to the regular dosing schedule. Do not double the dose to catch up.

Possible Side Effects:

• If any of the following serious side effects occur, stop giving Clomicalm and seek emergency veterinary medical attention; an allergic reaction (difficulty breathing; swelling of the lips, tongue or face, or hives); seizures; a fast or irregular heartbeat; high blood pressure; difficulty urinating; or fever with increased panting, muscle stiffness or muscle weakness.
• Continue giving Clomicalm and talk to your veterinarian if your pet has drowsiness or dizziness; dry mouth and eyes; constipation; panting; mild agitation, weakness or headache; nausea or loss of weight or appetite.

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